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Displaying drugs 201 - 225 of 14792 in total

Dalteparin

Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000....
Approved
Matched Description: … 5000 and about 90% of the material within the range of 2000-9000. ... LMWHs have a more predictable response, a greater bioavailability, and a longer anti-Xa half life than ... It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …

Magnesium

Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … as food processing and cooking vegetables (which are normally a rich source of magnesium). ... [A39559] Several factors and common behaviours reduce the availability of magnesium in the diet such ... [A32810] Despite the importance of magnesium and its availability via several food sources, an estimated …
Matched Mixtures name: … Herbs of Gold B Complex Plus Softgel ... Hvp Chelated Cal/mag With Zinc and Vitamins C and D ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET …

Hypromellose

Hypromellose, or hydroxypropyl methylcellulose (HPMC) , is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations . It...
Approved
Matched Description: … binder in the process of granulation and in modified release formulations [A24840]. ... a drug in a controlled fashion, effectively increasing the duration of release of a drug to prolong ... Hypromellose, or hydroxypropyl methylcellulose (HPMC) [L1812], is a semisynthetic, inert, and viscoelastic …
Matched Mixtures name: … Rohto Sun and Sport …

Esketamine

Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness preceding suicide.[L5596,A175462] On March 5, 2019, the nasal spray drug, esketamine, also known as Spravato (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. Esketamine is the s-enantiomer of Ketamine. Ketamine...
Approved
Investigational
Matched Description: … Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness ... The intranasal route of administration for this drug allows for easy administration and a fast onset ... Esketamine is the s-enantiomer of [Ketamine]. …
Matched Categories: … Non-Competitive N-Methyl D-Aspartate (NMDA) Receptor Antagonists …

Benzydamine

Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal system. Although the indazole analogue benzydamine is a...
Approved
Matched Description: … It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal ... various physicochemical properties and pharmacologic activities that are different from those of traditional ... Although the indazole analogue benzydamine is a non-steroidal anti-inflammatory drug (NSAID), it has …
Matched Mixtures name: … Anti-inflammatory Lozenge (with antibacterial) (Eucalyptus and Menthol) ... Difflam plus ANAESTHETIC Sore Throat Lozenges (Sugar Free) Menthol and Eucalyptus Flavour …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Non COX-2 selective NSAIDS ... Anti-Inflammatory Agents, Non-Steroidal ... Antiinflammatory Preparations, Non-Steroids for Topical Use ... Mouthwashes and Gargles …

Olipudase alfa

Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Description: … [A251590] It is the first and only enzyme replacement therapy in the world for the treatment of Acid ... the abnormal accumulation of the primary ASM substrate, sphingomyelin. ... to hydrolyze sphingomyelin accumulated in body tissues, such as the lungs, liver, spleen, kidneys, and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Pemigatinib

Pemigatinib is a small molecule kinase inhibitor with antitumour activity. It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases that activate signalling pathways in tumour cells. FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a wide...
Approved
Investigational
Matched Description: … cancers including those of the urinary bladder, breast, ovary, prostate, endometrium, lung, and stomach ... physiological processes, such as cancer cell proliferation, enhanced angiogenesis, and evasion of cell ... [A198984] Deregulated FGFR signalling pathway can lead the development of oncogenes and tumour-promoting …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Piroxicam

A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Description: … A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in ... , and postoperative pain. ... treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Analgesics, Non-Narcotic …

Ginger oil

Approved
Experimental

Benoxaprofen

The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.
Approved
Withdrawn
Matched Description: … The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic ... The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Antiinflammatory and Antirheumatic Products ... Analgesics, Non-Narcotic ... Anti-Inflammatory Agents, Non-Steroidal …

Dornase alfa

Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Description: … Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. …
Matched Categories: … Enzymes and Coenzymes ... Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins …

Gefitinib

Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Description: … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Darolutamide

Darolutamide is a nonsteroidal androgen receptor antagonist for the treatment of castrate-resistant, non-metastatic prostate cancer (nmCRPC). This condition occurs in the majority of patients with advanced prostate cancer who have been treated with androgen receptor antagonists. Though prior treatment for prostate cancer has been successful for these patients, the cancer...
Approved
Investigational
Matched Description: … non-metastatic prostate cancer (nmCRPC). ... disease, increasing quality of life and life expectancy for those with advanced prostate cancer. ... [A189054,A189063] Darolutamide was developed by Bayer HealthCare Pharmaceuticals Inc. and approved by …
Matched Categories: … Antiandrogens, non-steroidal ... Hormone Antagonists and Related Agents ... Antineoplastic and Immunomodulating Agents …

Celecoxib

Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched Description: … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous ... therapeutic drugs in clinical trials for a variety of malignancies. ... [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... combinations of sulfonamides ... Analgesics, Non-Narcotic ... Anti-Inflammatory Agents, Non-Steroidal ... tramadol and celecoxib …

Anidulafungin

Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366. There is preliminary evidence that it has a similar safety profile to caspofungin.
Approved
Investigational
Matched Description: … Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Sparfloxacin

Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
Approved
Investigational
Withdrawn
Matched Description: … deactivation, and transcription. ... DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Etodolac

Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Description: … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. ... Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Analgesics, Non-Narcotic …

Meloxicam

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and...
Approved
Vet approved
Matched Description: … Meloxicam is available in oral, transdermal, and intravenous formulations. ... pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. ... effects, however, this is a topic of controversy. …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... bupivacaine and meloxicam ... Antiinflammatory and Antirheumatic Products ... Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Analgesics, Non-Narcotic …

Tipranavir

Tipranavir is a sulfonamide-containing dyhydropyrone and a nonpeptidic protease inhibitor that targets the HIV protease. Tipranavir and ritonavir are coadministered to treat HIV.
Approved
Investigational
Matched Description: … Tipranavir and ritonavir are coadministered to treat HIV. ... Tipranavir is a sulfonamide-containing dyhydropyrone and a nonpeptidic protease inhibitor that targets …

Sodium chromate Cr-51

Approved

Nimesulide

Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has...
Approved
Investigational
Withdrawn
Matched Description: … Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic ... and primary dysmenorrhoea in adolescents and adults above 12 years old. ... and antipyretic properties. …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Antiinflammatory and Antirheumatic Products ... Analgesics, Non-Narcotic ... Topical Products for Joint and Muscular Pain ... Anti-Inflammatory Agents, Non-Steroidal …

Floctafenine

Floctafenine is an anti-inflammatory analgesic similar in action to aspirin. Floctafenine inhibits prostaglandin synthesis.
Approved
Withdrawn
Matched Categories: … Miscellaneous Analgesics and Antipyretics ... Analgesics, Non-Narcotic ... Non COX-2 selective NSAIDS ... Anti-Inflammatory Agents, Non-Steroidal …

Pancuronium

A bis-quaternary steroid that is a competitive nicotinic antagonist. As a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and on histamine release.
Approved
Matched Description: … neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and …

Clotiazepam

Clotiazepam is a thienodiazepine, not approved for sale in the U.S. or Canada, but has been approved in the U.K. It is a schedule IV drug in Canada.
Approved
Illicit
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …

Glycine

A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Approved
Nutraceutical
Vet approved
Matched Description: … A non-essential amino acid. ... It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Blood Substitutes and Perfusion Solutions …
Displaying drugs 201 - 225 of 14792 in total