Sarafloxacin hydrochlorideProduct ingredient for Sarafloxacin
- Name
- Sarafloxacin hydrochloride
- Drug Entry
- Sarafloxacin
Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.
- Accession Number
- DBSALT001657
- Structure
- Synonyms
- Sarafloxacin HCl
- UNII
- I36JP4Q9DF
- CAS Number
- 91296-87-6
- Weight
- Average: 421.83
Monoisotopic: 421.1004755 - Chemical Formula
- C20H18ClF2N3O3
- InChI Key
- KNWODGJQLCISLC-UHFFFAOYSA-N
- InChI
- InChI=1S/C20H17F2N3O3.ClH/c21-12-1-3-13(4-2-12)25-11-15(20(27)28)19(26)14-9-16(22)18(10-17(14)25)24-7-5-23-6-8-24;/h1-4,9-11,23H,5-8H2,(H,27,28);1H
- IUPAC Name
- 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- SMILES
- Cl.OC(=O)C1=CN(C2=CC=C(F)C=C2)C2=CC(N3CCNCC3)=C(F)C=C2C1=O
- External Links
- ChemSpider
- 50726
- ChEMBL
- CHEMBL542157
- Predicted Properties
Property Value Source Water Solubility 0.105 mg/mL ALOGPS logP 0.29 ALOGPS logP 0.56 Chemaxon logS -3.6 ALOGPS pKa (Strongest Acidic) 5.74 Chemaxon pKa (Strongest Basic) 8.68 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 72.88 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 99.9 m3·mol-1 Chemaxon Polarizability 37.15 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon