Lanthanum carbonate hydrateProduct ingredient for Lanthanum carbonate
- Name
- Lanthanum carbonate hydrate
- Drug Entry
- Lanthanum carbonate
Lanthanum carbonate is a phosphate binder marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects. It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to dietary phosphate and preventing its absorption in the intestine.2
- Accession Number
- DBSALT001176
- Structure
- Synonyms
- Dilanthanum tricarbonate hydrate / Lanthanum (III) carbonate hydrate / Lanthanum carbonate pentahydrate / Lanthanum carbonate tetrahydrate
- UNII
- 490D9F069T
- CAS Number
- 54451-24-0
- Weight
- Average: 529.895
Monoisotopic: 529.80921 - Chemical Formula
- C3H8La2O13
- InChI Key
- PKOQIYFBOVTYOH-UHFFFAOYSA-H
- InChI
- InChI=1S/3CH2O3.2La.4H2O/c3*2-1(3)4;;;;;;/h3*(H2,2,3,4);;;4*1H2/q;;;2*+3;;;;/p-6
- IUPAC Name
- dilanthanum(3+) tetrahydrate tricarbonate
- SMILES
- O.O.O.O.[La+3].[La+3].[O-]C([O-])=O.[O-]C([O-])=O.[O-]C([O-])=O
- External Links
- Human Metabolome Database
- HMDB0013711
- Predicted Properties
Property Value Source Water Solubility 31.0 mg/mL ALOGPS logP 0.65 ALOGPS logP 0.25 Chemaxon logS -1.2 ALOGPS pKa (Strongest Acidic) 3.5 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 63.19 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 31.17 m3·mol-1 Chemaxon Polarizability 3.52 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon