Reaction: Rizatriptan to 1 product
- Reaction
- Reaction type
- Oxidative deamination
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- inactive
- References
- Vyas KP, Halpin RA, Geer LA, Ellis JD, Liu L, Cheng H, Chavez-Eng C, Matuszewski BK, Varga SL, Guiblin AR, Rogers JD: Disposition and pharmacokinetics of the antimigraine drug, rizatriptan, in humans. Drug Metab Dispos. 2000 Jan;28(1):89-95. [Article]
- FDA Approved Drug Products: MAXALT (rizatriptan benzoate) tablets, for oral use and MAXALT-MLT (rizatriptan benzoate) orally disintegrating tablets (October 2019) [Link]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Amine oxidase [flavin-containing] A Not Available Not Available confirmed