Reaction: Promethazine to 1 product
- Reaction
- Reaction type
- Not Available
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- unknown
- References
- Nakamura K, Yokoi T, Inoue K, Shimada N, Ohashi N, Kume T, Kamataki T: CYP2D6 is the principal cytochrome P450 responsible for metabolism of the histamine H1 antagonist promethazine in human liver microsomes. Pharmacogenetics. 1996 Oct;6(5):449-57. [Article]
- Comments
- Not Available
- Enzymes
- Not Available