Adenosine receptor A3
Details
- Name
- Adenosine receptor A3
- Synonyms
- Not Available
- Gene Name
- ADORA3
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0000705|Adenosine receptor A3 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC VVCHPSDSLDTSIEKNSE
- Number of residues
- 318
- Molecular Weight
- 36184.175
- Theoretical pI
- 9.04
- GO Classification
- FunctionsG-protein coupled adenosine receptor activityComponentsintegral component of membrane / plasma membrane
- General Function
- G-protein coupled adenosine receptor activity
- Specific Function
- Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.
- Pfam Domain Function
- 7tm_1 (PF00001)
- Transmembrane Regions
- 15-37 49-72 85-106 127-148 178-198 232-255 262-284
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0010106|Adenosine receptor A3 (ADORA3) ATGCCCAACAACAGCACTGCTCTGTCATTGGCCAATGTTACCTACATCACCATGGAAATT TTCATTGGACTCTGCGCCATAGTGGGCAACGTGCTGGTCATCTGCGTGGTCAAGCTGAAC CCCAGCCTGCAGACCACCACCTTCTATTTCATTGTCTCTCTAGCCCTGGCTGACATTGCT GTTGGGGTGCTGGTCATGCCTTTGGCCATTGTTGTCAGCCTGGGCATCACAATCCACTTC TACAGCTGCCTTTTTATGACTTGCCTACTGCTTATCTTTACCCACGCCTCCATCATGTCC TTGCTGGCCATCGCTGTGGACCGATACTTGCGGGTCAAGCTTACCGTCAGATACAAGAGG GTCACCACTCACAGAAGAATATGGCTGGCCCTGGGCCTTTGCTGGCTGGTGTCATTCCTG GTGGGATTGACCCCCATGTTTGGCTGGAACATGAAACTGACCTCAGAGTACCACAGAAAT GTCACCTTCCTTTCATGCCAATTTGTTTCCGTCATGAGAATGGACTACATGGTATACTTC AGCTTCCTCACCTGGATTTTCATCCCCCTGGTTGTCATGTGCGCCATCTATCTTGACATC TTTTACATCATTCGGAACAAACTCAGTCTGAACTTATCTAACTCCAAAGAGACAGGTGCA TTTTATGGACGGGAGTTCAAGACGGCTAAGTCCTTGTTTCTGGTTCTTTTCTTGTTTGCT CTGTCATGGCTGCCTTTATCTATCATCAACTGCATCATCTACTTTAATGGTGAGGTACCA CAGCTTGTGCTGTACATGGGCATCCTGCTGTCCCATGCCAACTCCATGATGAACCCTATC GTCTATGCCTATAAAATAAAGAAGTTCAAGGAAACCTACCTTTTGATCCTCAAAGCTTGT GTGGTCTGCCATCCCTCTGATTCTTTGGACACAAGCATTGAGAAGAATTCTGAGTAG
- Chromosome Location
- 1
- Locus
- 1p13.2
- External Identifiers
Resource Link UniProtKB ID P0DMS8 UniProtKB Entry Name AA3R_HUMAN GenBank Protein ID 349449 GenBank Gene ID L20463 GenAtlas ID ADORA3 HGNC ID HGNC:268 - General References
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Drug Relations
- Drug Relations
DrugBank ID Name Drug group Pharmacological action? Actions Details DB01223 Aminophylline approved yes antagonist Details DB00640 Adenosine approved, investigational yes agonist Details DB05511 Piclidenoson investigational unknown Details DB00824 Enprofylline approved, experimental unknown inhibitor Details DB12010 Fostamatinib approved, investigational unknown antagonist Details DB00201 Caffeine approved yes antagonist Details