Monocarboxylate transporter 6
Details
- Name
- Monocarboxylate transporter 6
- Synonyms
- MCT 5
- MCT 6
- MCT5
- MCT6
- Monocarboxylate transporter 5
- Solute carrier family 16 member 5
- Gene Name
- SLC16A5
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0000769|Monocarboxylate transporter 6 MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILT AVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF SFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFL HCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCV YILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAF ASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMD QFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQ KKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRT SHEWLLWPKAVLQAKQTALGWNSPT
- Number of residues
- 505
- Molecular Weight
- 54993.04
- Theoretical pI
- 8.28
- GO Classification
- Functionslactate transmembrane transporter activity / monocarboxylic acid transmembrane transporter activity / symporter activityProcessesmonocarboxylic acid transport / plasma membrane lactate transportComponentsintegral component of plasma membrane / membrane
- General Function
- Symporter activity
- Specific Function
- Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
- Pfam Domain Function
- MFS_1 (PF07690)
- Transmembrane Regions
- 18-38 54-74 81-101 111-131 138-158 172-192 240-260 275-295 306-326 330-350 368-388 397-417
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0010270|Monocarboxylate transporter 6 (SLC16A5) ATGCCCCAGGCCCTGGAGCGTGCAGATGGCAGCTGGGCCTGGGTGGTGCTGCTGGCCACC ATGGTGACCCAGGGCCTCACCCTGGGCTTCCCCACGTGTATCGGCATCTTCTTCACTGAA TTGCAATGGGAGTTCCAGGCCAGCAACAGCGAGACCTCTTGGTTCCCCTCCATCCTCACG GCTGTGCTCCACATGGCAGGGCCCCTGTGCAGCATCCTGGTGGGACGCTTCGGCTGCCGA GTGACCGTGATGCTGGGGGGCGTGCTGGCCAGCCTGGGCATGGTGGCCAGCTCCTTCTCT CACAACCTCAGCCAGCTCTACTTCACAGCAGGATTCATCACAGGCCTGGGCATGTGCTTC AGCTTCCAGTCAAGCATCACGGTGCTGGGCTTCTACTTTGTCCGCCGGCGGGTGCTGGCC AACGCGCTGGCCTCGATGGGCGTCTCCCTGGGCATCACCCTCTGGCCGCTGCTCTCCCGC TACCTTCTGGAGAACCTGGGCTGGAGGGGTACCTTCCTTGTCTTCGGCGGGATCTTTCTC CACTGCTGCATCTGCGGGGCCATCATAAGGCCTGTGGCCACCAGTGTGGCCCCTGAGACC AAAGAATGTCCCCCGCCACCTCCCGAGACACCTGCACTTGGCTGCCTGGCTGCATGCGGC CGGACCATCCAGCGCCACCTGGCCTTCGACATCCTGCGGCACAACACAGGCTACTGCGTG TACATACTGGGTGTGATGTGGTCCGTCCTGGGCTTCCCACTGCCACAAGTCTTCCTGGTG CCATATGCCATGTGGCACAGCGTGGACGAGCAGCAGGCAGCCCTCCTCATCTCCATCATC GGCTTCAGCAACATCTTCCTGAGGCCCCTAGCCGGGCTGATGGCAGGACGGCCGGCCTTT GCTAGCCACCGCAAGTACCTGTTCAGCCTGGCACTCCTGCTCAATGGGCTCACTAACCTG GTGTGTGCGGCATCAGGTGACTTCTGGGTGCTCGTGGGCTACTGCCTGGCGTACAGCGTG TCCATGAGTGGCATCGGCGCCCTCATCTTCCAGGTTCTCATGGACATCGTCCCCATGGAT CAGTTCCCCAGAGCCCTGGGACTCTTCACTGTCCTGGACGGCCTTGCTTTCCTCATCTCC CCACCACTGGCCGGGTTGCTCCTGGACGCCACCAACAACTTTAGCTATGTTTTCTACATG TCCAGCTTCTTCCTCATCTCAGCTGCCCTCTTCATGGGTGGCAGCTTCTACGCCCTGCAG AAGAAGGAGCAAGGCAAGCAGGCTGTCGCGGCGGATGCCCTGGAGCGGGATCTTTTCTTG GAAGCCAAAGACGGTCCTGGGAAGCAACGGTCCCCTGAGATCATGTGCCAGTCTTCCCGC CAGCCACGTCCAGCTGGCGTCAATAAGCATCTTTGGGGATGTCCTGCCTCCTCCAGGACC AGCCATGAGTGGCTCTTATGGCCAAAGGCGGTACTGCAGGCCAAGCAAACGGCTCTGGGC TGGAATAGCCCTACCTGA
- Chromosome Location
- 17
- Locus
- 17q25.1
- External Identifiers
Resource Link UniProtKB ID O15375 UniProtKB Entry Name MOT6_HUMAN GenBank Protein ID 2463630 GenBank Gene ID U59299 GenAtlas ID SLC16A5 HGNC ID HGNC:10926 - General References
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