ABBV-CLS-7262
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- ABBV-CLS-7262
- DrugBank Accession Number
- DB18407
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 782.48
Monoisotopic: 781.1357666 - Chemical Formula
- C29H37Cl2F2N3NaO12P
- Synonyms
- Sodium ({(2S)-1,4-bis[2-(4-chloro-3- fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen phosphate - 2-amino-2- (hydroxymethyl)propane-1,3-diol (1/1/1)
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- BN9FN5629V
- CAS number
- Not Available
- InChI Key
- RQOVFRFZOGXABE-IPMISBIPSA-M
- InChI
- InChI=1S/C25H27Cl2F2N2O9P.C4H11NO3.Na/c26-17-3-1-15(9-19(17)28)37-12-22(32)30-24-5-7-25(8-6-24,21(11-24)39-14-40-41(34,35)36)31-23(33)13-38-16-2-4-18(27)20(29)10-16;5-4(1-6,2-7)3-8;/h1-4,9-10,21H,5-8,11-14H2,(H,30,32)(H,31,33)(H2,34,35,36);6-8H,1-3,5H2;/q;;+1/p-1/t21-,24?,25?;;/m0../s1
- IUPAC Name
- sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2-yl]oxy}methyl hydrogen phosphate
- SMILES
- [Na+].NC(CO)(CO)CO.OP([O-])(=O)OCO[C@H]1CC2(CCC1(CC2)NC(=O)COC1=CC=C(Cl)C(F)=C1)NC(=O)COC1=CC=C(Cl)C(F)=C1
References
- General References
- Not Available
- External Links
- Wikipedia
- Fosigotifator
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2, 3 Active Not Recruiting Treatment Amyotrophic Lateral Sclerosis (ALS) 1 2, 3 Enrolling by Invitation Treatment Amyotrophic Lateral Sclerosis (ALS) 1 1 Active Not Recruiting Treatment Amyotrophic Lateral Sclerosis (ALS) 1 1 Completed Treatment Healthy Volunteers (HV) 2 1 Recruiting Basic Science Healthy Volunteers (HV) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 0.89 Chemaxon pKa (Strongest Acidic) 1.43 Chemaxon pKa (Strongest Basic) 3.21 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 8 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 155.48 Å2 Chemaxon Rotatable Bond Count 15 Chemaxon Refractivity 139.36 m3·mol-1 Chemaxon Polarizability 59.08 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 21, 2023 22:23 / Updated at February 05, 2024 00:29