BMS-986278
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- BMS-986278
- DrugBank Accession Number
- DB18011
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 445.52
Monoisotopic: 445.232519118 - Chemical Formula
- C22H31N5O5
- Synonyms
- (1s,3s)-3-((2-methyl-6-(1-methyl-5-(((methyl(propyl)carbamoyl)oxy)methyl)-1h-1,2,3-triazol-4-yl)pyridin-3-yl)oxy)cyclohexane-1-carboxylic acid
- Cyclohexanecarboxylic acid, 3-((2-methyl-6-(1-methyl-5-((((methylpropylamino)carbonyl)oxy)methyl)-1h-1,2,3-triazol-4-yl)-3-pyridinyl)oxy)-, (1s,3s)-
- External IDs
- BMS 986278
- BMS-986278
- BMS986278
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 4UN9AOU6G8
- CAS number
- 2170126-74-4
- InChI Key
- UEUNDURNLYLSNB-HOTGVXAUSA-N
- InChI
- InChI=1S/C22H31N5O5/c1-5-11-26(3)22(30)31-13-18-20(24-25-27(18)4)17-9-10-19(14(2)23-17)32-16-8-6-7-15(12-16)21(28)29/h9-10,15-16H,5-8,11-13H2,1-4H3,(H,28,29)/t15-,16-/m0/s1
- IUPAC Name
- (1S,3S)-3-({2-methyl-6-[1-methyl-5-({[methyl(propyl)carbamoyl]oxy}methyl)-1H-1,2,3-triazol-4-yl]pyridin-3-yl}oxy)cyclohexane-1-carboxylic acid
- SMILES
- CCCN(C)C(=O)OCC1=C(N=NN1C)C1=CC=C(O[C@H]2CCC[C@@H](C2)C(O)=O)C(C)=N1
References
- General References
- Not Available
- External Links
- ChemSpider
- 115009679
- ChEMBL
- CHEMBL5087506
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Recruiting Treatment Idiopathic Pulmonary Fibrosis (IPF) 1 3 Recruiting Treatment Progressive Pulmonary Fibrosis 1 2 Completed Treatment Pulmonary Fibrosis 1 1 Completed Treatment Healthy Volunteers (HV) 8 1 Completed Treatment Idiopathic Pulmonary Fibrosis (IPF) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 2.48 Chemaxon pKa (Strongest Acidic) 4.31 Chemaxon pKa (Strongest Basic) 3.26 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 7 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 119.67 Å2 Chemaxon Rotatable Bond Count 9 Chemaxon Refractivity 127.45 m3·mol-1 Chemaxon Polarizability 47.33 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 06, 2023 21:02 / Updated at September 07, 2023 18:09