Bocidelpar
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Bocidelpar
- DrugBank Accession Number
- DB16906
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 460.497
Monoisotopic: 460.197377226 - Chemical Formula
- C25H27F3N2O3
- Synonyms
- Hexanoic acid, 3-methyl-6-(2-((5-methyl-2-(4-(trifluoromethyl)phenyl)-1h-imidazol-1-yl)methyl)phenoxy)-, (3r)-
- External IDs
- ASP-0367
- ASP0367
- MA-0211
- MTB-1
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Product Ingredients
Ingredient UNII CAS InChI Key Bocidelpar sulfate LWF2PR5DHD 2095128-21-3 KQZUMUQVRPOWSE-UHFFFAOYSA-N
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- FKO8A7AD54
- CAS number
- 2095128-20-2
- InChI Key
- FMOPHFSPINWSOV-QGZVFWFLSA-N
- InChI
- InChI=1S/C25H27F3N2O3/c1-17(14-23(31)32)6-5-13-33-22-8-4-3-7-20(22)16-30-18(2)15-29-24(30)19-9-11-21(12-10-19)25(26,27)28/h3-4,7-12,15,17H,5-6,13-14,16H2,1-2H3,(H,31,32)/t17-/m1/s1
- IUPAC Name
- (3R)-3-methyl-6-[2-({5-methyl-2-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl}methyl)phenoxy]hexanoic acid
- SMILES
- C[C@H](CCCOC1=CC=CC=C1CN1C(C)=CN=C1C1=CC=C(C=C1)C(F)(F)F)CC(O)=O
References
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2, 3 Active Not Recruiting Treatment Primary Mitochondrial Myopathy 1 1 Completed Basic Science Healthy Volunteers (HV) 1 1 Completed Basic Science Healthy Volunteers (HV) / Hepatic Impairment 1 1 Completed Basic Science Healthy Volunteers (HV) / Impaired Renal Function 1 1 Completed Treatment Healthy Volunteers (HV) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.000455 mg/mL ALOGPS logP 5.71 ALOGPS logP 4.7 Chemaxon logS -6 ALOGPS pKa (Strongest Acidic) 4.21 Chemaxon pKa (Strongest Basic) 6.31 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 64.35 Å2 Chemaxon Rotatable Bond Count 11 Chemaxon Refractivity 130.5 m3·mol-1 Chemaxon Polarizability 46.01 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at August 31, 2022 18:37 / Updated at May 20, 2024 12:05