Metronidazole benzoate
Star0
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Metronidazole benzoate
- DrugBank Accession Number
- DB15759
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 275.264
Monoisotopic: 275.090605911 - Chemical Formula
- C13H13N3O4
- Synonyms
- 2-(2-Methyl-5-nitroimidazol-1-yl)ethyl benzoate
- Benzoyl metronidazole
- Benzoylmetronidazole
- Metronidazol benzoilo
- Metronidazole benzoate
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Treatment of Amoebiasis •••••••••••• Treatment of Giardiasis •••••••••••• Prevention of Postoperative infections •••••••••••• Treatment of Trichomonal urethritis •••••••••••• Treatment of Trichomonas vaginitis •••••••••••• - Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image DIARSET NX- M SUSPENSION Metronidazole benzoate (5 g) + Nifuroxazide (4 g) Suspension Oral ARBOFARMA S.A.S. 2007-07-30 Not applicable Colombia KRODEX F COMPUESTO SUSPENSIÓN Metronidazole benzoate (5 g) + Nifuroxazide (4 g) Suspension Oral COASPHARMA S.A.S. 2007-02-06 Not applicable Colombia METRO F SUSPENSION Metronidazole benzoate (5 g) + Nifuroxazide (4 g) Suspension Oral COLOMPACK S.A. 2018-09-25 Not applicable Colombia METRONIF SUSPENSION Metronidazole benzoate (5 g) + Nifuroxazide (4 g) Suspension Oral PROCAPS S.A. 2006-11-10 Not applicable Colombia METRONIF SUSPENSION Metronidazole benzoate (5 g) + Nifuroxazide (4 g) Suspension Oral PROCAPS S.A. 2006-11-10 Not applicable Colombia
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- A355C835XC
- CAS number
- 13182-89-3
- InChI Key
- CUUCCLJJOWSASK-UHFFFAOYSA-N
- InChI
- InChI=1S/C13H13N3O4/c1-10-14-9-12(16(18)19)15(10)7-8-20-13(17)11-5-3-2-4-6-11/h2-6,9H,7-8H2,1H3
- IUPAC Name
- 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl benzoate
- SMILES
- CC1=NC=C(N1CCOC(=O)C1=CC=CC=C1)[N+]([O-])=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 75079
- 103866
- ChEBI
- 50688
- ChEMBL
- CHEMBL1466172
- ZINC
- ZINC000000163922
- Wikipedia
- Metronidazole
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Completed Treatment Chronic Periodontitis (Disorder) 1 1 Completed Not Available Healthy Volunteers (HV) 1 1 Completed Basic Science Healthy Volunteers (HV) 1 1 Completed Treatment Bacterial Infections 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Suspension Oral 2.5 g Suspension Oral 5 g Suspension Oral Powder Not applicable 1 g/1g Suspension Oral Suspension Oral 125 MG/5ML Injection Intravenous Suspension Oral 8 g Suspension Oral 200 ml/5ml - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.236 mg/mL ALOGPS logP 1.71 ALOGPS logP 2.04 Chemaxon logS -3.1 ALOGPS pKa (Strongest Basic) 3.27 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 87.26 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 70.04 m3·mol-1 Chemaxon Polarizability 27.2 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at August 17, 2020 21:00 / Updated at February 21, 2021 18:55