Luteolin
Star1
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Luteolin
- DrugBank Accession Number
- DB15584
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 286.2363
Monoisotopic: 286.047738052 - Chemical Formula
- C15H10O6
- Synonyms
- Digitoflavone
- Flacitran
- Luteoline
- Luteolol
- Salifazide
- External IDs
- C.I. Natural Yellow 2
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- KUX1ZNC9J2
- CAS number
- 491-70-3
- InChI Key
- IQPNAANSBPBGFQ-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H
- IUPAC Name
- 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
- SMILES
- OC1=CC(O)=C2C(=O)C=C(OC2=C1)C1=CC=C(O)C(O)=C1
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0005800
- KEGG Compound
- C01514
- ChemSpider
- 4444102
- BindingDB
- 7459
- ChEBI
- 15864
- ChEMBL
- CHEMBL151
- ZINC
- ZINC000018185774
- PDBe Ligand
- LU2
- Wikipedia
- Luteolin
- PDB Entries
- 3sz1 / 4dew / 4dgn / 4hkn / 4qxv / 4qya / 5auu / 5ii2 / 5ndf / 6m8a … show 5 more
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 0 Unknown Status Treatment Carcinoma / Tongue Neoplasms 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.138 mg/mL ALOGPS logP 2.73 ALOGPS logP 2.4 Chemaxon logS -3.3 ALOGPS pKa (Strongest Acidic) 6.57 Chemaxon pKa (Strongest Basic) -5.4 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 107.22 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 74.89 m3·mol-1 Chemaxon Polarizability 27.73 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 177.2712465 predictedDarkChem Lite v0.1.0 [M-H]- 178.4553465 predictedDarkChem Lite v0.1.0 [M-H]- 177.3187465 predictedDarkChem Lite v0.1.0 [M-H]- 164.22876 predictedDeepCCS 1.0 (2019) [M+H]+ 179.2523465 predictedDarkChem Lite v0.1.0 [M+H]+ 179.3243465 predictedDarkChem Lite v0.1.0 [M+H]+ 179.1528465 predictedDarkChem Lite v0.1.0 [M+H]+ 166.58702 predictedDeepCCS 1.0 (2019) [M+Na]+ 178.6766465 predictedDarkChem Lite v0.1.0 [M+Na]+ 179.2203465 predictedDarkChem Lite v0.1.0 [M+Na]+ 178.5841465 predictedDarkChem Lite v0.1.0 [M+Na]+ 172.94615 predictedDeepCCS 1.0 (2019)
Drug created at December 10, 2019 18:52 / Updated at June 12, 2020 16:53