Riboflavin tetrabutyrate
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Riboflavin tetrabutyrate
- DrugBank Accession Number
- DB14727
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 656.733
Monoisotopic: 656.305743633 - Chemical Formula
- C33H44N4O10
- Synonyms
- Riboflavin 2',3',4',5'-tetrabutyrate
- Riboflavin tetrabutyrate
- Riboflavin, 2',3',4',5'-tetrabutanoate
- Vitamin B2 tetrabutyrate
- External IDs
- SDBS-7805
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Aronamin Gold Riboflavin tetrabutyrate (2.5 mg/1) + Ascorbic acid (70 mg/1) + Fursultiamine (50 mg/1) + Hydroxocobalamin acetate (5.22 ug/1) + alpha-Tocopherol acetate (20 mg/1) Tablet, film coated Oral OASIS TRADING 2018-11-20 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Aronamin Gold Riboflavin tetrabutyrate (2.5 mg/1) + Ascorbic acid (70 mg/1) + Fursultiamine (50 mg/1) + Hydroxocobalamin acetate (5.22 ug/1) + alpha-Tocopherol acetate (20 mg/1) Tablet, film coated Oral OASIS TRADING 2018-11-20 Not applicable US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- F211C9MSGY
- CAS number
- 752-56-7
- InChI Key
- MJNIWUJSIGSWKK-BBANNHEPSA-N
- InChI
- InChI=1S/C33H44N4O10/c1-7-11-25(38)44-18-24(46-27(40)13-9-3)30(47-28(41)14-10-4)23(45-26(39)12-8-2)17-37-22-16-20(6)19(5)15-21(22)34-29-31(37)35-33(43)36-32(29)42/h15-16,23-24,30H,7-14,17-18H2,1-6H3,(H,36,42,43)/t23-,24+,30-/m0/s1
- IUPAC Name
- (2R,3S,4S)-1,2,4-tris(butanoyloxy)-5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}pentan-3-yl butanoate
- SMILES
- CCCC(=O)OC[C@@H](OC(=O)CCC)[C@@H](OC(=O)CCC)[C@H](CN1C2=C(C=C(C)C(C)=C2)N=C2C(=O)NC(=O)N=C12)OC(=O)CCC
References
- General References
- Not Available
- External Links
- ChemSpider
- 83186
- 2106328
- ChEBI
- 32097
- ChEMBL
- CHEMBL1325863
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tablet, film coated Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0092 mg/mL ALOGPS logP 3.72 ALOGPS logP 5.43 Chemaxon logS -4.8 ALOGPS pKa (Strongest Acidic) 6.04 Chemaxon pKa (Strongest Basic) -3.5 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 9 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 179.33 Å2 Chemaxon Rotatable Bond Count 21 Chemaxon Refractivity 169.79 m3·mol-1 Chemaxon Polarizability 68.42 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 275.9656493 predictedDarkChem Lite v0.1.0 [M-H]- 233.10173 predictedDeepCCS 1.0 (2019) [M+H]+ 277.7505493 predictedDarkChem Lite v0.1.0 [M+H]+ 234.92662 predictedDeepCCS 1.0 (2019) [M+Na]+ 277.4089493 predictedDarkChem Lite v0.1.0 [M+Na]+ 240.68904 predictedDeepCCS 1.0 (2019)
Drug created at December 15, 2018 23:00 / Updated at June 12, 2020 16:53