Trypanocidal Agents
- Name
- Trypanocidal Agents
- Accession Number
- DBCAT001101
- Description
Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.
- Drugs
Drug Drug Description Pentamidine An antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV. Posaconazole A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. Diminazene Diminazene, also known as Diminazine, 4,4'-(Diazoamino)benzamidine, 4,4'-(1-triazene-1,3-diyl)bis-benzenecarboximidamide, diminazine aceturate, or Diminazene aceturate, is a trypanocidal agent. Major brands of Diminazene are Berenil, Pirocide, Ganasag, and Azidin. This substance is a... Eflornithine An ornithine decarboxylase inhibitor used to prevent relapse of high-risk neuroblastoma in pediatric and adult patients Puromycin Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting... Nifurtimox An antiparasitic drug used for the treatment of Chagas disease (Trypanosoma cruzi infection). Benznidazole A trypanocidal agent used to treat Chagas disease. Melarsoprol Melarsoprol is under investigation in clinical trial NCT00330148 (Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis). Pafuramidine Investigated for use/treatment in pneumonia, trypanosomiasis, malaria, HIV infection, and infectious and parasitic disease (unspecified). Salicylhydroxamic Acid Not Available Suramin For treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms. Lonidamine Investigated for use/treatment in benign prostatic hyperplasia, prostate disorders, and cancer/tumors (unspecified). Homidium Homidium is a group II compound with trypanocidal effects. - Drugs & Drug Targets