Amplification of human APO(a) kringle 4-37 from blood lymphocyte DNA.
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Pfaffinger D, Mc Lean J, Scanu AM
Amplification of human APO(a) kringle 4-37 from blood lymphocyte DNA.
Biochim Biophys Acta. 1993 Nov 25;1225(1):107-9.
- PubMed ID
- 7848387 [ View in PubMed]
- Abstract
We have been able to amplify the lysine binding pocket region of human apo(a) kringle type 5 starting from the DNA isolated from peripheral blood lymphocytes. This development now permits the identification of Lp(a) mutants that by lacking their ability to bind to lysine/fibrin would have a lesser thrombogenic potential.