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Displaying drugs 126 - 150 of 13485 in total

Aminolevulinic acid

A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Approved
Matched Description: … A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. ... It is used as a photochemotherapy for actinic keratosis. [PubChem] …
Matched Categories: … Sensitizers Used in Photodynamic/radiation Therapy …

Dihydrostreptomycin

Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate.
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … )-a-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine ... N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-a-L-glucopyranosyl]-3-C-(hydroxymethyl …
Matched Description: … In humans, the use of dihydrostreptomycin has been associated with ototoxicity. ... The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate …

Tolevamer

Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched International brands: … Resonium A …
Matched Description: … It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines ... Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. ... It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Resonium A Pulver …

Alprostadil

Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Description: … In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection ... or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for ... Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator …
Matched Categories: … Drugs Used in Erectile Dysfunction …
Matched Products: … Muse 125 Mikrogramm - Stäbchen zur Anwendung in der Harnröhre ... Muse 250 Mikrogramm - Stäbchen zur Anwendung in der Harnröhre ... Muse 500 Mikrogramm - Stäbchen zur Anwendung in der Harnröhre …

Nitroglycerin

Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Description: … [A249965] Originally used to dynamite, its antianginal effects were identified in the late 1860s after ... [A180172] Nitroglycerin is used in a variety of different conditions, including angina pectoris due ... [L38369] that was first discovered in 1847. …
Matched Mixtures name: … Nitroglycerin In 5% Dextrose Inj.-400mcg/ml ... Nitroglycerin In 5% Dextrose Inj.-200mcg/ml ... Nitroglycerin In 5% Dextrose Inj.-100mcg/ml …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Vasodilators Used in Cardiac Diseases …
Matched Products: … Nitroglycerin in Dextrose ... Nitroglycerin In Dextrose …

Tenofovir alafenamide

Tenofovir alafenamide is a novel tenofovir prodrug developed in order to improve renal safety when compared to the counterpart tenofovir disoproxil. Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and intestinal...
Approved
Matched Description: … Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when ... by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and intestinal diffusion ... compared to the counterpart [tenofovir disoproxil]. …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …

Potassium hydroxide

Potassium hydroxide, also known as lye is an inorganic compound with the chemical formula KOH. Also commonly referred to as caustic potash, it is a potent base that is marketed in several forms including pellets, flakes, and powders. It is used in various chemical, industrial and manufacturing applications. Potassium hydroxide...
Approved
Matched Description: … Potassium hydroxide is used in food to adjust pH, as a stabilizer, and as a thickening agent. ... [L1943] In addition to the above uses, potassium hydroxide is also used in making soap, as an electrolyte ... Recently, it has been studied for efficacy and tolerability in the treatment of warts. …
Matched Mixtures name: … NUTRIFLEX PERI IN 2000ML TWIN-FLEX ... NUTRIFLEX PLUS IN 1000ML TWIN FLEX ... NUTRIFLEX PLUS IN 2000ML TWIN FLEX …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MIRACLE WATER 3 in 1 …

Methotrexate

Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Description: … Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis ... effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in ... [A180322,L7144,L7147,L7150,L7180] Due to the toxic effects of methotrexate, it is indicated for treatment …
Matched Categories: … OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … METOTREXATO 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... INJ METHOTREXATE CS 50MG IN 2ML ... INJ METHOTREXATE CS 1000MG IN 10ML …

Cupric sulfate

Cupric sulfate is a salt created by treating cupric oxide with sulfuric acid. This forms as large, bright blue crystals containing five molecules of water (CuSO4∙5H2O) and is also known as blue vitriol. The anhydrous salt is created by heating the hydrate to 150 °C (300 °F). Cupric sulfate is...
Approved
Matched Description: … The average daily intake of copper in the USA is approximately 1 mg Cu with the diet being a primary ... Some of its secondary uses are as a raw material in the preparation of other copper compounds, as a reagent ... After zinc and iron, copper is the third most abundant trace element found in the human body. …
Matched Mixtures name: … One-A-day Advance Men's ... One A Day Advance Adults ... One A Day Advance Adults 50+ …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Paliperidone

Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin...
Approved
Matched Iupac: … [4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a] …
Matched Description: … It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination ... The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. ... intramuscular injection, and a twice-yearly gluteal injection. …
Matched Products: … Palibon 25 mg Depot-Injektionssuspension in einer Fertigspritze ... Palibon 50 mg Depot-Injektionssuspension in einer Fertigspritze ... Palibon 75 mg Depot-Injektionssuspension in einer Fertigspritze …

Dopamine

One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Approved
Matched Description: … Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating ... One of the catecholamine neurotransmitters in the brain. ... A family of receptors (receptors, dopamine) mediate its action. …
Matched Mixtures name: … Dopamine Hydrochloride in Dextrose ... Dopamine Hydrochloride in Dextrose ... Dopamine Hydrochloride in Dextrose …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Monoamine Oxidase A Substrates …
Matched Products: … Dopamine Hci In 5% Dextrose ... Dopamine Hydrochloride in Dextrose …

Turoctocog alfa

Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … acid 720, and a monoclonal antibody binding C-terminal to this position is used in the purification ... Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence ... [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] …
Matched Products: … NOVOEIGHT® 1500 UI POLVO ESTERIL PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …

Amylocaine

Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute . Elsewhere in English...
Approved
Withdrawn
Matched Description: … Elsewhere in English speaking countries it was referred to as Stovaine, given the meaning of the French ... Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes ... Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized …

Icatibant

Icatibant is a synthetic decapeptide with 5 nonproteinogenic amino acid antagonist targeting the B2 receptors with a similar affinity to bradykinin. It is resistant to bradykinin-cleaving enzyme degradation and has a potency of 2-3 times higher than earlier B2 receptors antagonists, thus representing a new class of medication.[A4017,A263041] It was...
Approved
Investigational
Matched Description: … [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a ... , thus demonstrating bradykinin involvement in the disease pathophysiology. ... Icatibant is a synthetic decapeptide with 5 nonproteinogenic amino acid antagonist targeting the BMatched Categories: … Drugs Used in Hereditary Angioedema …
Matched Products: … Icatibant STADA 30 mg Injektionslösung in einer Fertigspritze ... Icatibant Hikma 30 mg Injektionslösung in einer Fertigspritze ... Icatibant ratiopharm 30 mg Injektionslösung in einer Fertigspritze …

Magnesium

Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … [A19349] The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite ... [A39559] Several factors and common behaviours reduce the availability of magnesium in the diet such ... as food processing and cooking vegetables (which are normally a rich source of magnesium). …
Matched Mixtures name: … One A Day Tab ... Extra Once A Day ... Once A Day Tablets …
Matched Products: … MAGNEROT A 500 BEUTEL ... MAGNEROT A 120 KAUTABL ... Port A Mins Super Magnesium 188 …

Loperamide

Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Description: … [L42785] The drug was first synthesized in 1969 and used medically in 1976. ... [A251610, A251625] However, loperamide is associated with a risk for experiencing a range of adverse ... Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating …
Matched Mixtures name: … Doc in the Box All Day Supply ... Meds on the Go …
Matched Products: … A D ... Imodium A-D ... Vaprino A-D …

Alectinib

Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC cells. Inhibition of ALK...
Approved
Investigational
Matched Description: … Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma ... It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 ... Approved under accelerated approval in 2015, alectinib is indicated for use in patients who have progressed …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Factor IX Complex (Human)

Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting ... factors found in functioning human plasma. ... factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients experiencing …

Allopurinol

Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals . Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially ... Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective ... This disease has been well-documented in historical medical records and appears in the biographies of …

Ibuprofen

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched Description: … was in 1960 while researching for a safer alternative for aspirin. ... in the UK in 1969 and USA in 1974. ... [A39076] On the available products, ibuprofen is administered as a racemic mixture. …
Matched Mixtures name: … Doc in the Box All Day Supply ... Ibuprofen Cold and Sinus A P J ... Meds on the Go …

Pralidoxime

Pralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. If given within 24 hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase.
Approved
Vet approved
Matched Description: … Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible ... inactivation of the enzyme. ... by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … PAM-A INJECTION 500 mg/ampoule …

Fludrocortisone

Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched Iupac: … 1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Fludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace ... , and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position of ... missing endogenous corticosteroids in patients with adrenal insufficiency. …

Benzoyl peroxide

Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … Benzoyl peroxide is a commonly used drug in topical treatments for acne. ... [L33314] After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically ... [L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient …
Matched Mixtures name: … Clear Proof Acne System The Go Set ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit …
Matched Products: … All-IN-one ... Oxy On-The-Go Acne Stick ... Dual-shave 2 In 1 …

Somatotropin

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Description: … [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone ... secreted by the somatotropic cells of the anterior pituitary gland. ... [A228183] Growth hormone plays an essential role in growth regulation during childhood as well as other …
Matched Products: … POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE ... SciTropin A Solution for Injection 5 mg/1.5 ml ... SciTropin A Solution for Injection 10 mg/1.5 ml …

Vitamin E

In 1922, vitamin E was demonstrated to be an essential nutrient . Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active . Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage . The antioxidant effects...
Approved
Nutraceutical
Vet approved
Matched Description: … The antioxidant effects are currently being researched for use in the treatment of diseases causing bone ... In 1922, vitamin E was demonstrated to be an essential nutrient[A32448]. ... Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol …
Matched Mixtures name: … Aces Formula/formule A A S ... ONE A DAY TABLET ... Extra Once A Day …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 126 - 150 of 13485 in total