Bupranolol hydrochlorideProduct ingredient for Bupranolol
- Name
- Bupranolol hydrochloride
- Drug Entry
- Bupranolol
Bupranolol is a non-selective beta blocker with potency similar to propanolol. It does not have intrinsic sympathomimetic activity (ISA), but does have strong membrane stabilizing activity.
- Accession Number
- DBSALT000905
- Structure
- Synonyms
- Bupranolol HCl
- External IDs
- B 1312 / B-1312 / KL 255 / KL-255
- UNII
- DTC2G3GDPL
- CAS Number
- 15148-80-8
- Weight
- Average: 308.24
Monoisotopic: 307.1105844 - Chemical Formula
- C14H23Cl2NO2
- InChI Key
- WJUUZHQWGKSLIJ-UHFFFAOYSA-N
- InChI
- InChI=1S/C14H22ClNO2.ClH/c1-10-5-6-12(15)13(7-10)18-9-11(17)8-16-14(2,3)4;/h5-7,11,16-17H,8-9H2,1-4H3;1H
- IUPAC Name
- 1-(tert-butylamino)-3-(2-chloro-5-methylphenoxy)propan-2-ol hydrochloride
- SMILES
- Cl.CC1=CC(OCC(O)CNC(C)(C)C)=C(Cl)C=C1
- External Links
- Predicted Properties
Property Value Source Water Solubility 0.143 mg/mL ALOGPS logP 3.14 ALOGPS logP 2.99 Chemaxon logS -3.3 ALOGPS pKa (Strongest Acidic) 14.09 Chemaxon pKa (Strongest Basic) 9.76 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 41.49 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 74.86 m3·mol-1 Chemaxon Polarizability 30.19 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon