Indecainide hydrochlorideProduct ingredient for Indecainide
- Name
- Indecainide hydrochloride
- Drug Entry
- Indecainide
Indecainide is a rarely used antidysrhythmic. Indecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.
- Accession Number
- DBSALT000880
- Structure
- Synonyms
- Indecainide HCl
- UNII
- M76V0B96L5
- CAS Number
- 73681-12-6
- Weight
- Average: 344.88
Monoisotopic: 344.1655411 - Chemical Formula
- C20H25ClN2O
- InChI Key
- NXNSCUZKMVYAJQ-UHFFFAOYSA-N
- InChI
- InChI=1S/C20H24N2O.ClH/c1-14(2)22-13-7-12-20(19(21)23)17-10-5-3-8-15(17)16-9-4-6-11-18(16)20;/h3-6,8-11,14,22H,7,12-13H2,1-2H3,(H2,21,23);1H
- IUPAC Name
- 9-{3-[(propan-2-yl)amino]propyl}-9H-fluorene-9-carboxamide hydrochloride
- SMILES
- Cl.CC(C)NCCCC1(C(N)=O)C2=CC=CC=C2C2=C1C=CC=C2
- External Links
- PubChem Compound
- 52194
- ChemSpider
- 47193
- ChEBI
- 774292
- ChEMBL
- CHEMBL1200341
- Predicted Properties
Property Value Source Water Solubility 0.000896 mg/mL ALOGPS logP 3.24 ALOGPS logP 3.26 Chemaxon logS -5.5 ALOGPS pKa (Strongest Acidic) 16.51 Chemaxon pKa (Strongest Basic) 10.4 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 55.12 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 94.05 m3·mol-1 Chemaxon Polarizability 35.59 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon