Tolterodine tartrateProduct ingredient for Tolterodine
- Name
- Tolterodine tartrate
- Drug Entry
- Tolterodine
Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
- Accession Number
- DBSALT000467
- Structure
- Synonyms
- Tolterodine tartrate
- External IDs
- PNU 200583E / PNU-200583E
- UNII
- 5T619TQR3R
- CAS Number
- 124937-52-6
- Weight
- Average: 475.5745
Monoisotopic: 475.257002543 - Chemical Formula
- C26H37NO7
- InChI Key
- TWHNMSJGYKMTRB-KXYUELECSA-N
- InChI
- InChI=1S/C22H31NO.C4H6O6/c1-16(2)23(17(3)4)14-13-20(19-9-7-6-8-10-19)21-15-18(5)11-12-22(21)24;5-1(3(7)8)2(6)4(9)10/h6-12,15-17,20,24H,13-14H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t20-;1-,2-/m11/s1
- IUPAC Name
- (2R,3R)-2,3-dihydroxybutanedioic acid; 2-[(1R)-3-[bis(propan-2-yl)amino]-1-phenylpropyl]-4-methylphenol
- SMILES
- [H][C@](O)(C(O)=O)[C@@]([H])(O)C(O)=O.[H][C@@](CCN(C(C)C)C(C)C)(C1=CC=CC=C1)C1=C(O)C=CC(C)=C1
- External Links
- PubChem Compound
- 443878
- ChemSpider
- 391966
- ChEMBL
- CHEMBL1200871
- Wikipedia
- Tolterodine
- Predicted Properties
Property Value Source Water Solubility 0.00534 mg/mL ALOGPS logP 5.39 ALOGPS logP 5.12 Chemaxon logS -4.8 ALOGPS pKa (Strongest Acidic) 10.28 Chemaxon pKa (Strongest Basic) 11.01 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 23.47 Å2 Chemaxon Rotatable Bond Count 10 Chemaxon Refractivity 103.96 m3·mol-1 Chemaxon Polarizability 39.53 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon