Aminosalicylate sodium anhydrousProduct ingredient for Aminosalicylic acid
- Name
- Aminosalicylate sodium anhydrous
- Drug Entry
- Aminosalicylic acid
An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
- Accession Number
- DBSALT000354
- Structure
- Synonyms
- 4-aminosalicylate sodium / Anhydrous sodium aminosalicylate / p-aminosalicylate sodium / p-aminosalicylic acid sodium salt / para-aminosalicylate sodium / Sodium para-aminosalicylate
- UNII
- T9ZKL3TNQF
- CAS Number
- 133-10-8
- Weight
- Average: 175.1172
Monoisotopic: 175.024537738 - Chemical Formula
- C7H6NNaO3
- InChI Key
- FVVDKUPCWXUVNP-UHFFFAOYSA-M
- InChI
- InChI=1S/C7H7NO3.Na/c8-4-1-2-5(7(10)11)6(9)3-4;/h1-3,9H,8H2,(H,10,11);/q;+1/p-1
- IUPAC Name
- sodium 5-amino-2-carboxybenzen-1-olate
- SMILES
- [Na+].NC1=CC([O-])=C(C=C1)C(O)=O
- External Links
- KEGG Compound
- C08055
- PubChem Compound
- 2724368
- ChemSpider
- 20993
- ChEBI
- 2661
- ChEMBL
- CHEMBL1200966
- Wikipedia
- 4-Aminosalicylic_acid
- Predicted Properties
Property Value Source Water Solubility 32.4 mg/mL ALOGPS logP 0.62 ALOGPS logP 0.83 Chemaxon logS -0.73 ALOGPS pKa (Strongest Acidic) 3.68 Chemaxon pKa (Strongest Basic) 2.19 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 86.38 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 50.55 m3·mol-1 Chemaxon Polarizability 13.94 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon