Fluoxetine hydrochlorideProduct ingredient for Fluoxetine
- Name
- Fluoxetine hydrochloride
- Drug Entry
- Fluoxetine
Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).2 It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.13
- Accession Number
- DBSALT000087
- Structure
- Synonyms
- Not Available
- UNII
- I9W7N6B1KJ
- CAS Number
- 56296-78-7
- Weight
- Average: 345.787
Monoisotopic: 345.110726557 - Chemical Formula
- C17H19ClF3NO
- InChI Key
- GIYXAJPCNFJEHY-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H
- IUPAC Name
- methyl({3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl})amine hydrochloride
- SMILES
- Cl.CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
- External Links
- PubChem Compound
- 62857
- ChemSpider
- 56589
- ChEBI
- 145458
- ChEMBL
- CHEMBL1201082
- Wikipedia
- Fluoxetine
- Predicted Properties
Property Value Source Water Solubility 0.0017 mg/mL ALOGPS logP 4.09 ALOGPS logP 4.17 Chemaxon logS -5.3 ALOGPS pKa (Strongest Basic) 9.8 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 21.26 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 80.37 m3·mol-1 Chemaxon Polarizability 30.33 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon