Pulmonary Rifampicin- and Isoniazid-Resistant Tuberculosis

Drug	Drug Name	Drug Description
DB05154	Pretomanid	Part of a three-drug regimen used for the treatment of extensively drug-resistant and multidrug-resistant pulmonary tuberculosis.

Drug	Drug Name	Target	Type
DB05154	Pretomanid	Deazaflavin-dependent nitroreductase	enzyme
DB05154	Pretomanid	Solute carrier family 22 member 8	transporter
DB05154	Pretomanid	Cytochrome P450 3A4	enzyme
DB05154	Pretomanid	Fatty acid synthetase	target
DB05154	Pretomanid	Uncharacterized MFS-type transporter EfpA	target
DB05154	Pretomanid	Nucleoid-associated protein Lsr2	target
DB05154	Pretomanid	Cyd operon, Mycobacterium tuberculosis	target
DB05154	Pretomanid	Enoyl-[acyl-carrier-protein] reductase [NADH]	target

Drug	Drug Name	Phase	Status	Count