Iopofosine I-124
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Iopofosine I-124
- DrugBank Accession Number
- DB17127
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 634.626
Monoisotopic: 634.277432612 - Chemical Formula
- C29H53INO4P
- Synonyms
- 18-(p-(124i )-iodophenyl)octadecyl phosphocholine
- Ethanaminium, 2-((hydroxy((18-(4-(iodo-124i)phenyl)octadecyl)oxy)phosphinyl)oxy)-n,n,n-trimethyl-, inner salt
- External IDs
- (124I)-CLR1404
- 124I-CLR1404
- CLR-1404 I-124
- I-124-CLR1404
- NM-404 I-124
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 08W354EC17
- CAS number
- 873438-87-0
- InChI Key
- ZOAIEFWMQLYMTF-PEHXSSJGSA-N
- InChI
- InChI=1S/C29H53INO4P/c1-31(2,3)25-27-35-36(32,33)34-26-19-17-15-13-11-9-7-5-4-6-8-10-12-14-16-18-20-28-21-23-29(30)24-22-28/h21-24H,4-20,25-27H2,1-3H3/i30-3
- IUPAC Name
- 18-[4-(¹²⁴I)iodophenyl]octadecyl 2-(trimethylazaniumyl)ethyl phosphate
- SMILES
- C[N+](C)(C)CCOP([O-])(=O)OCCCCCCCCCCCCCCCCCCC1=CC=C([124I])C=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 9745713
- ChEMBL
- CHEMBL4297390
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Terminated Diagnostic High Grade Glioma: Glioblastoma (GBM) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 1.06e-05 mg/mL ALOGPS logP 4.38 ALOGPS logP 5.65 Chemaxon logS -7.8 ALOGPS pKa (Strongest Acidic) 1.88 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 58.59 Å2 Chemaxon Rotatable Bond Count 24 Chemaxon Refractivity 172.77 m3·mol-1 Chemaxon Polarizability 69.9 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at November 17, 2022 20:23 / Updated at December 01, 2022 11:35