Clonazoline
Star0
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Clonazoline
- DrugBank Accession Number
- DB15881
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 244.72
Monoisotopic: 244.0767261 - Chemical Formula
- C14H13ClN2
- Synonyms
- Clonazolina
- Clonazoline
- Clonazolinum
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination to treat Allergic rhinitis (ar) Combination Product in combination with: Fluocinolone acetonide (DB00591) •••••••••••• ••••• Used in combination to treat Allergic rhinosinusitis Combination Product in combination with: Fluocinolone acetonide (DB00591) •••••••••••• ••••• Used in combination to treat Ethmoid sinusitis Combination Product in combination with: Fluocinolone acetonide (DB00591) •••••••••••• ••••• Used in combination to treat Phlegm of the ear Combination Product in combination with: Fluocinolone acetonide (DB00591) •••••••••••• ••••• Used in combination to treat Respiratory disorders Combination Product in combination with: Fluocinolone acetonide (DB00591) •••••••••••• ••••• - Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Product Ingredients
Ingredient UNII CAS InChI Key Clonazoline hydrochloride 7WVH15JYKM 23593-08-0 JOJMOKBPTKPWER-UHFFFAOYSA-N
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- YH9K692U9S
- CAS number
- 17692-28-3
- InChI Key
- GPPLXTFJYCQMRB-UHFFFAOYSA-N
- InChI
- InChI=1S/C14H13ClN2/c15-13-6-5-10(9-14-16-7-8-17-14)11-3-1-2-4-12(11)13/h1-6H,7-9H2,(H,16,17)
- IUPAC Name
- 2-[(4-chloronaphthalen-1-yl)methyl]-4,5-dihydro-1H-imidazole
- SMILES
- ClC1=C2C=CC=CC2=C(CC2=NCCN2)C=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 168921
- ChEMBL
- CHEMBL2104096
- ZINC
- ZINC000000001193
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Spray Nasal - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0116 mg/mL ALOGPS logP 3.73 ALOGPS logP 2.8 Chemaxon logS -4.3 ALOGPS pKa (Strongest Basic) 10.18 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 24.39 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 70.32 m3·mol-1 Chemaxon Polarizability 26 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-0002-0090000000-e768ef1af2750b5c97d2 Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-0006-3090000000-59beb6637414ceb2823c Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-0002-0190000000-9733a5851e3924451d25 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-03di-2900000000-a8026f606c5163a836ac Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-004i-0900000000-9575e0fd60aafdbd0065 Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-001i-9400000000-5e6d398e46a509b1b6b9 Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 24, 2020 17:22 / Updated at February 21, 2021 18:55