Fludeoxyglucose
Star0
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Fludeoxyglucose is a radiopharmaceutical indicated for PET scans.
- Generic Name
- Fludeoxyglucose
- DrugBank Accession Number
- DB15107
- Background
Fludeoxyglucose is under investigation in clinical trial NCT03262389 (Comparison of F-18 FDG and C-11 Acetate PET in Multiple Myeloma).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 182.147
Monoisotopic: 182.059051617 - Chemical Formula
- C6H11FO5
- Synonyms
- Not Available
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- ZO2JV75L55
- CAS number
- 29702-43-0
- InChI Key
- AOYNUTHNTBLRMT-SLPGGIOYSA-N
- InChI
- InChI=1S/C6H11FO5/c7-3(1-8)5(11)6(12)4(10)2-9/h1,3-6,9-12H,2H2/t3-,4+,5+,6+/m0/s1
- IUPAC Name
- (2R,3S,4R,5R)-2-fluoro-3,4,5,6-tetrahydroxyhexanal
- SMILES
- OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](F)C=O
References
- General References
- AIFA: Efdege (Fluodeoxyglucose) Injection [Link]
- External Links
- ChemSpider
- 148702
- ChEBI
- 49135
- ChEMBL
- CHEMBL1908940
- ZINC
- ZINC000001846431
- Wikipedia
- Fluorodeoxyglucose_(18F)
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Completed Diagnostic Positron-Emission Tomography and Cone-Beam Computed Tomography 1 4 Recruiting Diagnostic Deep Vein Thrombosis / Lung Disorder / Pulmonary Embolism / Respiratory Diseases / Screening / Undefined / Venous Thromboembolism Diseases 1 4 Terminated Basic Science Abdominal Aortic Aneurysm (AAA) 1 2 Completed Diagnostic Cancer 1 2 Completed Diagnostic Multiple Myeloma (MM) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, solution Parenteral 1 GBq - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 139.0 mg/mL ALOGPS logP -1.8 ALOGPS logP -2.7 Chemaxon logS -0.12 ALOGPS pKa (Strongest Acidic) 12.25 Chemaxon pKa (Strongest Basic) -3 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 97.99 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 35.65 m3·mol-1 Chemaxon Polarizability 15.52 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-00ke-4900000000-4cddcdd49492d9027c21 Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-0a4i-9000000000-ba86c875a092d5c8a5a8 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-0avi-9000000000-97a70bb577ce5cdd1f31 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-03dl-9100000000-a93285cc5c6ddf3a10df Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-052f-9000000000-7b16fed320d58c285cef Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-0005-9000000000-c46b9f8769e60147d76d Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at May 20, 2019 14:50 / Updated at May 14, 2021 01:07