Blood Coagulation Factor Inhibitors
- Name
- Blood Coagulation Factor Inhibitors
- Accession Number
- DBCAT002052
- Description
Substances, usually endogenous, that act as inhibitors of blood coagulation. They may affect one or multiple enzymes throughout the process. As a group, they also inhibit enzymes involved in processes other than blood coagulation, such as those from the complement system, fibrinolytic enzyme system, blood cells, and bacteria.
- Drugs
Drug Drug Description Drotrecogin alfa A form of recombinant activated human protein C used to reduce mortality in patients with severe sepsis by inhibiting coagulation Factors V and VIII. Protein C A medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis. Antithrombin III human An alpha-2-glycoprotein used to prevent thromboembolisms in patients with hereditary antithrombin III deficiency. Protein S human A medication used for emergency reversal of coagulation factor deficiency in vitamin K antagonist therapy. - Drugs & Drug Targets