Abilities of peroxidases to catalyse peroxidase-oxidase oxidation of thiols.
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Svensson BE
Abilities of peroxidases to catalyse peroxidase-oxidase oxidation of thiols.
Biochem J. 1988 Dec 15;256(3):757-62.
- PubMed ID
- 2852004 [ View in PubMed]
- Abstract
The abilities of various peroxidases to catalyse the peroxidase-oxidase oxidation of seven aminothiols were studied. Cysteamine and cysteine esters were found to be peroxidase-oxidase substrates for eosinophil peroxidase and myeloperoxidase, whereas other thiols tested were inactive or poorly active with these peroxidases. With lactoperoxidase and horseradish peroxidase, all the tested thiols were inactive or poorly active as peroxidase-oxidase substrates. These studies suggest that a main reason for thiols being poor peroxidase-oxidase substrates is because these thiols are poor peroxidatic substrates.
DrugBank Data that Cites this Article
- Drug Enzymes
Drug Enzyme Kind Organism Pharmacological Action Actions Cysteamine Myeloperoxidase Protein Humans UnknownSubstrateDetails